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. Author manuscript; available in PMC: 2022 May 26.
Published in final edited form as: Curr Biol. 2022 Apr 20;32(10):2300–2308.e4. doi: 10.1016/j.cub.2022.03.078

Figure 2.

Figure 2.

Global analysis of protein distribution. (A) Analysis of correlation between enrichment in different cell fractions. Bars indicate the correlation coefficient in relative abundance (median normalized abundance in the given fraction relative to whole cells) between each of two fractions as indicated on the XY axes. Body refers to cell bodies from which the MB has been removed. (B) Proportion of proteins significantly enriched (p<0.05) in one compartment versus another based on binomial test. The category A>B indicates proteins that are significantly more abundant in the first versus second sample as indicated in the legend (blue: more abundant in MB than in cell body red: more abundant in anterior than in posterior). Uniform indicates proportion of proteins showing no significant different in abundance between the two samples being compared. B>A indicates proteins that are significantly more abundant in the second sample (cell body or posterior) than in the first sample (MB or anterior) for each of the two comparisons. (C) Protein families represented in the differentially enriched gene sets described in panel B. Further information relating to this figure is provided in Figure S2, which indicates protein families that are differentially enriched between individual pairs of samples.