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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Exp Hematol. 2022 Mar 17;110:34–38. doi: 10.1016/j.exphem.2022.03.005

Figure 2. CRLF2 overexpression is associated with reduced B cell differentiation in B-ALL patient samples.

Figure 2.

(A) In two CRLF2-overexpressing B-ALL patient samples (DS-ALL 839 and non-DS ALL 105127-R) demonstrating both pro-B and pre-B populations, the high-CRLF2 mean fluorescence intensity (MFI) quartile demonstrated a significantly higher mean proportion of pro-B cells (p=0.024). (B) Representative flow plots showing CRLF2 overexpression correlates with a less differentiated immunophenotype in B-ALL patient samples 839 (DS) and 105127-R (non-DS).

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