Table 2.
Medication | Action mechanism | Half-life | Indication (package insert) | Presentation | Dosage |
---|---|---|---|---|---|
Omalizumab | Anti-IgE | 26 days | CSU, allergic asthma | Ampoule-vial with lyophilized powder 100 mg | 300 mg SC every 4 weeks |
Dupilumab | Anti-IL-4, IL-13 | 7 days | Moderate to severe AD | Pre-filled syringe, 300 mg | I: 600 mg SC, without 0 |
M: 300 mg SC, every 2 weeks | |||||
Rituximab | Anti- B Lymphocytes | 3 weeks | Moderate to severe PV, RA, Leukemia, Lymphomas, Vasculitis | Ampoule-vial with lyophilized powder 100 mg/10 mL or 500 mg/50 m L | 2 doses of 1000 mg with a 14-day intervala |
Dose recommended for RA.