Table 5.
Smoking duration within TP53 htSNP haplotypes among 1037 subjects.
| Number | Haplotypea | Frequency | OR (95% CI) |
OR (95% CI) |
OR (95% CI) |
|---|---|---|---|---|---|
| Never | ≤20 (years) | >20 (years) | |||
| 1 | AGCCG | 0.4915 | 1.0 | 1.26 (0.68–2.34) | 1.90 (1.17–3.09)b |
| 2 | CCCGC | 0.2228 | 1.0 | 1.61 (0.90–2.87) | 2.22 (1.47–3.37)b |
| 3 | ACTCG | 0.0694 | 1.0 | 2.18 (0.83–5.72) | 2.16 (0.99–4.72) |
| 4 | CCCCG | 0.0562 | 1.0 | 1.72 (0.56–5.24) | 2.65 (1.08–6.51)b |
| 5 | ACCCG | 0.0405 | 1.0 | 1.01 (0.27–3.83) | 1.60 (0.64–4.00) |
| 6 | CCCCC | 0.0367 | 1.0 | 1.64 (0.41–6.58) | 1.30 (0.44–3.85) |
| 7 | AGCGC | 0.0159 | 1.0 | 2.17 (0.30–15.76) | 7.02 (0.91–53.99) |
| 8 | CGCCG | 0.0119 | 1.0 | 0.77 (0.05–13.12) | 0.84 (0.10–7.07) |
| 9 | ACCGC | 0.0112 | 1.0 | – | – |
| 10 | Rare | 0.0394 | 1.0 | 1.44 (0.22–9.53) | 4.34 (1.21–15.48)b |
a
SNP order: rs12951053-rs1042522-rs8079544-rs12602273-rs8064946.
b
Boldface indicates statistical significance (p value < 0.05).