Table 2.
The Ctrough, percentage, and methylation index of arsenic species in plasma from pregnant and non-pregnant women treated with arsenic trioxide (ATO), mean (range).
| iAs | DMA | MMA | tAs | PMI | SMI | ||
|---|---|---|---|---|---|---|---|
| Pregnant patients (n = 3) | Ctrough (ng/ml) | 17.31 (14.13–19.14) | 24.01 (16.89–28.65) | 23.4 2 (13.60–22.42) | 64.74 (54.53–78.26) | ||
| Percentage (%) | 26.74 (23.00–34.21) | 37.08 (30.98–46.64) | 36.18 (30.36–41.71) | ||||
| Methylation index | 1.35 (1.02–1.71) | 1.02 (0.81–1.54) | |||||
| Non-pregnant patients (n = 5) | Ctrough (ng/ml) | 16.53 (9.83–20.14) | 18.19 (9.19–23.28) | 18.41 (15.35–21.84) | 53.13 (44.67–58.87) | ||
| Percentage (%) | 31.11 (19.38–45.08) | 34.24 (20.57–45.9) | 34.65 (26.58–40.86) | ||||
| Methylation index | 1.11 (0.76–1.79) | 0.99 (0.60–1.71) |
Ctrough, trough concentration; iAs, inorganic arsenic; MMA, monomethylarsonic acid; DMA, dimethylarsinic acid; tAs, total arsenic, tAs = iAs + DMA + MMA. Percentage (%). (Concentrations of arsenic species/Concentration of tAs) × 100%. PMI, primary methylation index (MMA/iAs); SMI, secondary methylation index (DMA/MMA).