Table 1.
Patient characteristics
| Total | Non-HGI group | HGI group | P value | |
|---|---|---|---|---|
| Number of patients | 104 | 52 | 52 | |
| Age, median (range) | 60 (23-88) | 55 (23-85) | 66 (35-88) | .032* |
| FIGO (2008) | .966 | |||
| IB1 | 5 | 2 | 3 | |
| IB2 | 10 | 6 | 4 | |
| IIA2 | 3 | 1 | 2 | |
| IIB | 31 | 15 | 16 | |
| IIIA | 2 | 1 | 1 | |
| IIIB | 43 | 21 | 22 | |
| IVA | 10 | 6 | 4 | |
| Initial tumor size (cm), median (range) | 5.5 (1.5-9.2) | 5.5 (1.5-8.9) | 5.5 (2.3-9.2) | .834 |
| Histology | .473 | |||
| Squamous cell carcinoma | 94 | 47 | 47 | |
| Adenocarcinoma | 9 | 4 | 5 | |
| Adenosquamous cell carcinoma | 1 | 1 | 0 | |
| EBRT dose (Gy), median (range) | 50 (40-50.4) | 50 (40-50.4) | 50 (42-50.4) | .191 |
| BT dose (Gy), median (range) | 24 (12-36) | 24 (12-30) | 24 (12-36) | .296 |
| Type of BT | .463 | |||
| Intracavitary brachytherapy | 9 | 12 | ||
| IC/IS | 43 | 40 | ||
| Chemotherapy | <.002* | |||
| Concomitant chemotherapy | 74 | 45 | 29 | |
| Nonchemotherapy | 30 | 7 | 23 | |
| Follow-up time (mo), median (range) | 32.6 (4.6-147.2) | 50.4 (9.7-147.2) | 25.4 (4.6-52.7) | <.001* |
Abbreviations: BT = brachytherapy; EBRT = external beam radiation therapy; FIGO = International Federation of Gynaecology and Obstetrics; HGI = hyaluronate gel injection; IC/IS = intracavitary and interstitial brachytherapy.
⁎
Statistically significant.