Table 5.
Risk factors for secondary CNS relapse in peripheral T-cell lymphomas.
| Risk factors | Secondary CNS relapse (n = 16 pts) |
PTCL without CNS involvement (n = 1,011 pts) |
p |
|---|---|---|---|
| B symptoms | |||
| Yes | 12 | 495 | 0.035 |
| No | 4 | 516 | |
| Extranodal site | |||
| 0–1 | 8 | 811 | |
| 2 | 8 | 200 | 0.008 |
| Soft tissue involvement | |||
| Yes | 4 | 39 | 0.003 |
| No | 12 | 972 | |
| Testicular involvement | |||
| Yes | 1 | 3 | 0.046 |
| No | 15 | 1008 | |
| Bone marrow involvement | |||
| Yes | 3 | 191 | 0.988 |
| No | 13 | 820 | |
| Gastrointestinal involvement | |||
| Yes | 3 | 103 | 0.309 |
| No | 13 | 908 | |
| Paaranasal sinuses | |||
| Yes | 1 | 10 | 0.159 |
| No | 15 | 1,001 | |
| Lung involvement | |||
| Yes | 3 | 99 | 0.282 |
| No | 13 | 912 | |
| Pleural involvement | |||
| Yes | 0 | 20 | 0.426 |
| No | 16 | 991 | |
| Bone involvement | |||
| Yes | 2 | 44 | 0.194 |
| No | 14 | 967 | |
| Skin involvement | |||
| Yes | 4 | 215 | 0.723 |
| No | 12 | 796 | |
| Kidney involvement | |||
| Yes | 1 | 6 | 0.093 |
| No | 15 | 1,005 |