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. Author manuscript; available in PMC: 2022 May 26.
Published in final edited form as: Stat Methods Med Res. 2019 Apr 9;29(2):541–567. doi: 10.1177/0962280219841082

Table 3.

Covariates for patients with complete observations over all cycles (sample 1).

Variables 0 1 2 3 4

Age ≥80 years 604 (95) 32 (5)
Weight loss > 10% 631 (99) 5 (1)
ECOG performance status 123 (19) 381 (60) 100 (16) 11 (2) 21 (3)
Bilirubin >35, > 50 μmol/L 630 (99) 1 (0) 5 (1)
Treatment line 3, >3 547 (86) 46 (7) 43 (7)
Toxicity grades Vomiting 567 (89) 54 (8) 13 (2) 2 (0)
Nausea 344 (54) 226 (36) 60 (9) 6 (1)
Diarrhea 363 (57) 218 (34) 49 (8) 6 (1)
Asthenia 97 (15) 368 (58) 150 (24) 21 (3)
Neutropenia 444 (70) 111 (17) 67 (11) 9 (1) 5 (1)
Thrombopenia 524 (82) 104 (16) 6 (1) 1 (0) 1 (0)
Anemia 343 (54) 257 (40) 36 (6)

Note: Percentages are shown in parentheses.