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. 2022 May 12;10:887885. doi: 10.3389/fped.2022.887885

Table 5.

Risk factors of late readmission associated with characteristics on first PICU admission.

First PICU admission of characteristics Late readmission
(N = 70)
Control group
(N = 206)
p
Age (y), median (IQR) 1.25 (0.50–4.44) 1.25 (0.55–4.62) 0.100
Male sex, n (%) 38 (54.29) 111 (53.88) 0.927
Weight (kg), median (IQR) 10.35 (6.23–17) 11.65 (7.59–18.25) 0.099
With chronic conditions, n (%) 37 (52.86) 32 (15.53) <0.001*
Strongkids scores on admission, median (IQR) 3 (2–3) 2 (1–2) <0.001*
Admission primary diagnostic category, n (%) 0.021*
  Respiratory 31 (44.29) 89 (43.20)
  Neurologic 6 (8.56) 19 (9.22)
  Cardiovascular 9 (12.86) 17 (8.25)
  Infectious 11 (15.71) 25 (12.14)
  Trauma 1 (1.42) 22 (10.68)
  Tumor 3 (4.29) 3 (1.46)
  Hemorrhage/coagulopathy 3 (4.29) 11 (5.34)
  Urinary 3 (4.29) 9 (4.37)
  Other 3 (4.29) 11 (5.33)
Sedation medications, n (%) 46 (65.70) 99 (48.05) 0.031*
Vasopressors, n (%) 34 (48.57) 49 (23.79) 0.001*
Corticosteroids, n (%) 31 (44.3) 67 (32.52) 0.103
Invasive mechanical ventilation, n (%) 39 (55.71) 60 (29.12) 0.001*
Continuous renal replacement therapy, n (%) 19 (27.1) 35 (16.99) 0.077
PELOD 2 score, median (IQR) 6.12 (2.24–9.07) 5.12 (2.22–6.13) 0.246
First PICU length of stay in weeks, n (%) 0.001*
  <2 30 (42.86) 144 (69.90)
 ≥ 2 40 (57.14) 62 (30.10)
FSS at discharge, n (%) 0.069
  Normal function 42 (60) 165 (80.10)
  Mild dysfunction 13 (18.57) 20 (9.71)
  Moderate dysfunction 7 (10) 10 (4.85)
  Severe dysfunction 7 (10) 9 (4.37)
  Very severe dysfunction 1 (1.4) 2 (0.97)

IQR, interquartile range; PELOD 2 score, Pediatric Logistic Organ Dysfunction 2 score; FSS, Functional Status Scale.

*Significant risk factor in the multivariable analysis (p < 0.05).