ARdY mice develop subcutaneous obesity on a high-fat diet (HFD) due to reduced visceral-fat growth
(A) Body weight of 15-week-old mice fed either a standard diet or an HFD (n = 6).
(B) Lean mass of 15-week-old mice fed either a standard diet or an HFD as determined by MRI (n = 6).
(C) Total fat mass of 15-week-old mice fed either a standard diet or an HFD as determined by MRI (n = 6).
(D) Visceral and subcutaneous depot weights of 15-week-old mice on standard diet (n = 6).
(E) Visceral and subcutaneous depot weights of 15-week-old mice on HFD (n = 6).
(F) Fat distribution of 15-week-old mice on standard diet or HFD (n = 6).
Statistical significance in (A)–(E) was determined by ordinary one-way ANOVA with Tukey’s multiple comparisons test. Statistical significance in (F) was determined by an unpaired two-tailed Student’s t test. F, female; A, ARdY; M, male; Sub, subcutaneous; Vis, visceral.