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. 2022 May 12;10:856159. doi: 10.3389/fped.2022.856159

TABLE 3.

Design characteristics of the 10 studies describing external validation of BPD prediction models.

Study Country Study design Years of data Study population Timing of BPD Intended moment of model use Model validated
El Faleh et al. (17) Switzerland Registry 2014–2015 BW < 1,501 g and/or GA between 23 0/7 and 31 6/7 weeks DOL28 or PMA36 1 day El Faleh et al. (17)
Shim et al. (15) Korea Registry 2017 BW < 1,500 g and GA ≥ 22 weeks PMA36 1 h Shim et al. (15)
Bhattacharjee et al. (18) United States Retrospective cohort 2012–2013 BW < 1,500 g PMA36 3 day RSS
Lee et al. (20) Korea Registry 2013–2016 BW < 1,500 g and GA 22–32 weeks PMA36 1 h CRIB II; CRIB II-BE
Sullivan et al. (23) United States Retrospective cohort 2004–2014 BW < 1,500 g PMA36 12 h, 1 day, 7 day aHRC-24h, aHRC-7d, SNAP-II, CRIB-II
Gursoy et al. (24) Turkey Prospective cohort 2012 GA ≤ 32 weeks and BW ≤ 1,500 g DOL28 3 day BPD-TM score
May et al. (28) United Kingdom Retrospective cohort 1995–1998 BW < 1,500 g and GA < 33 weeks DOL28 or PMA36 2 day Simple pulmonary score
Henderson-Smart et al. (29) Australia, New Zealand Registry 2000–2001 GA 22–31 weeks PMA36 At birth Henderson-Smart et al. (29)
Kim et al. (30) Korea Prospective cohort 2000–2001 BW < 1,500 g PMA36 4 day, 7 day, 10 day SMUMRV; Yoder model (55)
Chien et al. (31) Canada Registry 1996–1997 GA ≤ 32 weeks PMA36 12 h SNAP-II + GA, SGA, sex, low Apgar score, and outborn status

BPD, bronchopulmonary dysplasia; BPD-TM, bronchopulmonary dysplasia test measure; BW, birth weight; CRIB, Clinical Risk Indicator fores; CRIB II-BE, Clinical Risk Indicator fores omitting base excess; DOL, days of life; GA, gestational age; HRC, heart rate characteristics; aHRC-24h, average first day HRC index; aHRC-7d, average first week HRC index within 7 days of birth; PMA, postmenstrual age; RSS, respiratory severity score; SGA, small for gestational age; SMUMRV, modified respiratory variables; SNAP-II, Score for Neonatal Acute Physiology-II.