TABLE 2.

Laboratory parameters of patients with hepatitis and hepatitis with liver fibrosis caused by HBV, HCV, and HEV infections.

Variables	Controls	HBV		HCV		HEV
		Hepatitis	Hepatitis + fibrosis	Hepatitis	Hepatitis + Fibrosis	Hepatitis	Hepatitis + fibrosis
Gender M/F	41/47	31/15	7/15	28/19	8/5	31/19	9/18
Age	56.00 (38.50–66.75)	41.50 (32.75–51.50)	55.00 (40.00–69.00)	53.00 (46.00–58.00)	55.00 (46.00–71.00)	53.00 (48.75–67.00)	59.00 (51.00–68.00)
ALT (U/L)	19.95 (16.85–25.5)	45.50 (25.00–86.00)	42.00 (28.00–241.50)	38.00 (21.00–68.00)	39.00 (21.00–81.00)	46.00 (21.00–75.00)	77.00 (32.25–233.50)
AST (U/L)	21.00 (18.80–25.97)	33.50 (25.75–57.75)	51.00 (32.00–244.50)*	36.00 (25.00–55.00)	37.00 (24.00–97.50)	55. 50 (28.00–131.25)	55.00 (33.00–108.00)
ALB (g/L)	15.20 (11.90–19.30)	46.55 (39.85–48.67)	36.10 (31.55–40.75)*	45.50 (41.70–46.40)	31.30 (29.50–39.00)*	38.90 (36.85–42.20)	31.40 (28.10–37.60)
Dbil (mmol/L)	2.70 (2.23–3.37)	5.25 (4.07–7.40)	11.50 (5.05–106.75)*	6.00 (3.90–7.37)	14.20 (8.55–33.15)*	6.20 (3.40–12.20)	14.70 (8.20–57.30)
Tbil (mmol/L)	15.20 (11.90–19.20)	15.00 (12.33–23.50)	19.00 (12.50–24.50)	17.00 (12.00–22.00)	34.00 (18.50–63.00)*	16.00 (10.87–27.75)	34.00 (19.00–63.00)
HA (ng/mL)	57 (45.00–84.00)	68.46 (37.46–102.25)	87.00 (67.00–231.79)*	81.50 (40.85–122.23)	109.00 (99.00–727.27)*	79.00 (71.00–98.50)	120.17 (92.00–503.65)*
sTim-3 (ng/mL)	7.69 (6.74–10.22)	13.29 (7.75–17.28)	22.76 (12.82–37.53)*	13.86 (11.48–18.64)	33.06 (16.36–39.30)*	14.77 (9.79–29.79)	28.90 (17.95–35.94)*

ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; Dbil, direct bilirubin; Tbil, total bilirubin; HA, hyaluronic acid; HBV, hepatitis B virus; HCV, hepatitis C virus; HEV, hepatitis E virus.*Significant differences in hepatitis and liver fibrosis in each parameter in the same virus infection (P < 0.05).