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. 2022 May 12;9:880909. doi: 10.3389/fmed.2022.880909

TABLE 3.

Comparison of the positive rate of sTim-3 and HA to distinguish hepatitis from hepatitis with liver fibrosis.

Positive rate
Cut off Controls Hepatitis Hepatitis + fibrosis
sTim-3 19.45 ng/mL 0.00% 21.68% 66.13%
HA 110 ng/mL 0.00% 4.90% 35.48%
sTim-3 or HA 0.00% 25.87% 77.42%

The cut off for sTim-3 was determined by the Youden index of Figure 4E, and HA concentration greater than 110 ng/mL was considered positive (commonly used in clinical practice).