Table 4.
Cases aged 16–65 years diagnosed with Shigella flexneri and Shigella sonnei infections with no reported travel history, by sex, male-to-female ratio and percentage male for selected serotypes, England, 2003–2013
| Organism | Serotype | Sex,m:f ratio and percentage male | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | Total | P valuea |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Shigella flexneri | All | Female | 77 | 88 | 97 | 95 | 112 | 102 | 110 | 121 | 107 | 76 | 66 | 1051 | <0.001 |
| Male | 65 | 73 | 92 | 95 | 101 | 121 | 137 | 204 | 208 | 257 | 349 | 1702 | |||
| Ratio | 0.8 | 0.8 | 0.9 | 1.0 | 0.9 | 1.2 | 1.2 | 1.7 | 1.9 | 3.4 | 5.3 | 1.6 | |||
| Percentage (95% CI) | 45.8 (37.4–54.3) | 45.3 (37.5–53.4) | 48.7 (41.4–56.0) | 50.0 (42.7–57.3) | 47.4 (40.6–54.4) | 54.3 (47.5–60.9) | 55.5 (49.0–61.8) | 62.8 (57.3–68.0) | 66 (60.5–71.2) | 77.2 (72.3–81.6) | 84.1 (80.2–87.5) | 61.8 (60.0–63.6) | |||
| PT 2a | Female | 4 | 7 | 4 | 4 | 2 | 4 | 3 | 3 | 7 | 14 | 14 | 66 | <0.001 | |
| Male | 3 | 2 | 5 | 4 | 0 | 4 | 7 | 6 | 21 | 42 | 74 | 168 | |||
| Ratio | 0.8 | 0.3 | 1.3 | 1.0 | 0.0 | 1.0 | 2.3 | 2.0 | 3.0 | 3.0 | 5.3 | 2.5 | |||
| Percentage (95% CI) | 42.9 (9.9–81.6) | 22.2 (2.8–60.0) | 55.6 (21.2–86.3) | 50.0 (15.7–84.3) | 0 (0–84.2) | 50.0 (15.7–84.3) | 70.0 (34.8–93.3) | 66.7 (29.9–92.5) | 75.0 (55.1–89.3) | 75.0 (61.6–85.6) | 84.1 (74.8–91) | 71.8 (65.6–77.5) | |||
| PT 3a | Female | 3 | 0 | 2 | 1 | 0 | 2 | 1 | 0 | 1 | 11 | 15 | 36 | <0.001 | |
| Male | 2 | 1 | 1 | 0 | 7 | 4 | 4 | 8 | 23 | 82 | 170 | 302 | |||
| Ratio | 0.7 | ∞ | 0.5 | 0.0 | ∞ | 2.0 | 4.0 | ∞ | 23.0 | 7.5 | 11.3 | 8.4 | |||
| Percentage (95% CI) | 40.0 (5.3–85.3) | 100 (2.5–100) | 33.3 (0.8–90.6) | 0 (0–97.5) | 100 (59.0–100) | 66.7 (22.3–95.7) | 80 (28.4–99.5) | 100 (63.1–100) | 95.8 (78.9–99.9) | 88.2 (79.8–93.9) | 91.9 (87–95.4) | 89.3 (85.6–92.4) | |||
| Shigella sonnei | All | Female | 212 | 253 | 326 | 271 | 387 | 304 | 414 | 409 | 261 | 184 | 195 | 3216 | <0.001 |
| Male | 162 | 271 | 262 | 163 | 274 | 247 | 264 | 365 | 295 | 320 | 332 | 2955 | |||
| Ratio | 0.8 | 1.1 | 0.8 | 0.6 | 0.7 | 0.8 | 0.6 | 0.9 | 1.1 | 1.7 | 1.7 | 0.9 | |||
| Percentage (95% CI) | 43.3 (38.2–48.5) | 51.7 (47.3–56.1) | 44.6 (40.5–48.7) | 37.6 (33–42.3) | 41.5 (37.7–45.3) | 44.8 (40.6–49.1) | 38.9 (35.2–42.7) | 47.2 (43.6–50.7) | 53.1 (48.8–57.3) | 63.5 (59.1–67.7) | 63 (58.7–67.1) | 47.9 (46.6–49.1) |
CI, Confidence interval.
a
χ2 test for linear trend.
Ratios above a threshold of two or where the percentage male has a lower confidence interval above 50% are shaded.