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Workflow of hiPSC-based disease modeling and downstream multi-omics analysis
hiPSC-derived control and disease-specific cell lines are generated either from healthy individuals, patients, or via CRISPR-Cas9 editing. Genomics, transcriptomics, and/or proteomics analyses are performed for each experimental condition. Conditions are cross-compared and interpreted to elucidate disease mechanisms and identify potential therapeutic targets. Created with Biorender.com.
