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. 2022 May 12;9:868833. doi: 10.3389/fnut.2022.868833

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Copyright © 2022 Jiang, Zhang, Yao, Huang, Wang, Huang, He and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In CSDS mice, ginsenosides Rb1 increased SIRT1 expression in the hippocampus. (A) SIRT1 expression in the rat hippocampal DG area, as seen by IHC staining. region (200, bar = 100 μm; 400, bar = 50 μm); (B) The mean fluorescence intensities of SIRT1 in the DG region; (C) Western blotting for detecting the SIRT1 expression in the hippocampus. The entire data has been presented are means ± SEM; N = 4 mice per group. ^##p < 0.01, considerably varied from control; ^*p and ^**p < 0.05, and 0.01, considerably varied from CSDS group.