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. 2022 May 12;13:874826. doi: 10.3389/fneur.2022.874826

Table 3.

Supratotal resection of WHO grade III gliomas (literature review).

Number of patients Tumor classification (WHO grading) Definition of supratotal resection Number of supratotal resection case (%) Adjuvant therapy Clinical outcome Mean follow-up duration and outcomes
Motomura et al. (53) 9 WHO grade II glioma, WHO grade III glioma Tumor resection extending beyond the abnormal MRI-verified area, which indicated that the volume of the postoperative cavity was larger than the preoperative tumor volume 9 (100%) NA WMS-R, SLTA, FAB, WAIS-III NA
NA
Rossi et al. (70) 319 WHO grade II glioma, WHO grade III glioma Complete removal of any signal abnormalities, with the volume of the postoperative cavity larger than preoperative tumor volume 110 (35%) Chemoradiotherapy (17.6%), chemotherapy only (41.2%) Adjuvant treatment, anaplastic transformation, postop seizures, recurrence rate, OS, PFS, MPFS 6.8 years
PFS at 92 months; 94%

WHO, World Health Organization; WMS-R; Wechsler memory scale revised, SLTA; Standard Language Test of Aphasia, FAB; Frontal Assessment Battery, WAIS-III; the third version of Wechsler adult intelligence score; OS, overall survival; PFS, progression free survival; MPFS, malignant progression free survival, NA, not available.