TABLE 3.

The multivariate logistic regression analysis of variables associated with small ICH adjusted for age and male sex.

	Total cohort			Lobar ICH			Non-lobar ICH
	aOR	95% CI	p-value	aOR	95% CI	p-value	aOR	95% CI	p-value
Model 1: individual SVD markers*
Hypertension	1.38	0.53–3.60	0.511	1.70	0.28–10.32	0.567	1.42	0.43–4.76	0.567
Lobar ICH	0.34	0.16–0.73	0.006	–	–	–	–	–	–
WMH Fazekas score	1.06	0.85–1.33	0.606	1.12	0.76–1.64	0.574	1.05	0.79–1.40	0.743
Presence of lacune	1.81	0.89–3.68	0.099	1.01	0.21–4.85	0.989	2.08	0.91–4.78	0.085
CMB ≥ 5	1.62	0.77–3.41	0.205	4.18	0.79–22.25	0.094	1.36	0.56–3.28	0.495
Presence of cSS	0.53	0.14–2.03	0.356	0.53	0.08–2.32	0.325	–	–	1.00
Model 2: global SVD score*
Hypertension	1.54	0.60–3.94	0.370	1.80	0.32–9.99	0.503	1.60	0.50–5.16	0.431
Lobar ICH	0.36	0.17–0.76	0.008	–	–	–	–	–	–
Presence of cSS	0.55	0.15–2.03	0.372	0.41	0.08–2.03	0.410	–	–	1.00
Global SVD score	1.27	1.03–1.57	0.027	1.44	0.94–2.20	0.094	1.23	0.95–1.58	0.122

* Adjusted for age and male sex. aOR, adjusted odds ratio; CI, confidence interval; cSS, cortical superficial siderosis; CMB, cerebral microbleed; ICH, intracerebral hemorrhage; SVD, small vessel disease; WMH, white matter hyperintensity.