| BRD2 |
− Promotion of E2F-dependent cell cycle progression in HeLa and HEK293 cells |
110 and 111
|
| − Closure of the neural tube in mouse embryos |
112 and 113
|
| − Maintenance of the number of GABAergic neurons in the neocortex and the striatum of mice |
114
|
| − Assist of transcription in hyperacetylated chromatin (Property of histone-chaperone) |
77
|
| − Transcriptional activation of HOXA11 and D11 in HEK293 cells |
115
|
| − Enhancement of GATA1-mediated erythroid gene activation |
116
|
| − Interaction with LANA of KSHV that mediates episomal replication and persistence of viral genomes |
117 and 118
|
| BRD3 |
− Assist of transcription in hyperacetylated chromatin (Property of histone-chaperone) |
77
|
| − Transcriptional activation of HOXB3, B4, B5, B6, C8, C9, C10, A3, A5, A6, and A7 in HEK293 cells |
115
|
| − Enhancement of GATA1-mediated erythroid gene activation |
116
|
| − Carcinogenesis induced by BRD3-NUT fusion protein |
119
|
| BRD4 |
− Stimulation of G2/M transition in HeLa cells |
80
|
| − Cell cycle progression in P19 embryonal carcinoma cells |
81
|
| − Maintenance of inner cell mass in mouse blastocysts |
120
|
| − Transcriptional activation of Nanog required for maintaining the pluripotency of ES cells |
121
|
| − Release from a pause in transcription elongation |
122 and 123
|
| − Assist of transcription in hyperacetylated chromatin (Property of histone-chaperone) |
124
|
| − Transcriptional activation of c-Myc and Klf4 in NIH3T3 cells |
124
|
| − Transcriptional activation of HOXB2, B3, B4, B5, B6, B7, B8, A4, and C5 in HEK293 cells |
115
|
| − Transcriptional regulation of genes involved in learning and memory in mice |
125
|
| − Enhancement of INF-induced gene transcription |
126
|
| − Signal transducer of the cellular response to oxidative stress |
127
|
| − Prevention of splicing inhibition in heat stress-induced cells |
128
|
| − A gene bookmark for transcriptional reactivation in post-mitotic cells |
129 and 130
|
| − Carcinogenesis induced by BRD4-NUT fusion protein |
119 and 131
|
| − Interaction with LANA of KSHV that mediates episomal replication and persistence of viral genomes |
132 and 133
|
| − Tethering of BPV genome to host mitotic chromosomes |
134
|
| − Transcriptional regulation of E2 that mediates episomal maintenance and DNA replication of HPV genome |
135–137
|
| BRDT |
− Transcriptional regulation of genes responsible for meiotic progression during spermatogenesis |
126
|
| − Splicing machinery in testicular cells |
138
|
| − Chromatin remodelling in MEL, 3T3, and COS7 cells |
139–141
|
| − Histone replacement at post-meiotic stages during spermatogenesis |
125
|
