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. 2022 May 12;94(20):7339–7349. doi: 10.1021/acs.analchem.2c00765

Figure 1.

Figure 1

Schematic illustration of mRNA sequence mapping workflow. Partial RNase T1 digests are performed in conjunction with LC–MS/MS analysis for automated oligoribonucleotide annotation and identification prior to sequence mapping.