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. 2018 May 15;146(10):1312–1317. doi: 10.1017/S0950268818001206

Table 2.

Risk of thrombocytopenia according to bacterial species

Univariable analysis Multivariable analysesa
Odds ratio 95% Confidence interval Odds ratio 95% Confidence interval P value
E. coli and S. pneumoniae bacteraemia 1.0 Ref. 1.0 Ref.
S. aureus bacteraemia 1.1 0.7–1.7 1.2 0.7–1.9 0.58
Age, per 1 year increase 1.0 1.0–1.0 1.0 1.0–1.0 0.66
Male sex 1.5 1.0–2.1 1.9 1.2–2.9 0.01
Pulmonary disease 0.6 0.3–1.0 0.5 0.3–1.0 0.05
Kidney disease 1.7 1.0–2.9 2.0 1.0–3.8 0.04
Hypotensionb 3.2 1.9–5.6 1.8 0.9–3.6 0.13
Hypoperfusionc 1.9 1.3–2.9 1.4 0.8–2.2 0.23
Organ dysfunctiond 2.1 1.40–3.0 1.6 1.0–2.5 0.08
ICU care 3.7 2.1–6.7 2.0 0.9–4.4 0.11
a

Estimated by logistic regression in 462 subjects with complete information, adjusted for all other variables in the table.

b

Defined as systolic blood pressure <90 mmHg and/or treatment with vasopressors.

c

Defined as any lactate >3.2 mmol/l or base excess ⩽−5 (in patients without chronic kidney failure).

d

Defined as either kidney dysfunction (increase >45 µmol/l in S-creatinine in patients without chronic kidney dysfunction or CRRT or dialysis treatment), liver dysfunction (S-bilirubin >45 mmol/l in patients without chronic liver disease or diagnosis of acute pancreatitis, cholecystitis or cholangitis), hypoxemia (oxygen saturation <87% or <79% if pneumonia or mechanical ventilation); altered mental status; coagulation dysfunction (INR>1.5 or APTT>60 s in patients without warfarin or heparin treatment).