FIGURE 1.
Development of new Cdk5 inhibitors. (A) Structures of four potential Cdk5 inhibitors: 25–106, 25–143, 25–107, and 25–132 (B). Synthesis of novel inhibitor, 25–106 (C). Regio-isomers are synthesized under strong or less basic conditions.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.