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Lactobacillus. sp. can protect the liver and intestine against MTX-induced toxicity. (A) Experiment design. (B, C) Representative H&E staining of liver tissues and histological score, Scale bar, 100μm. (D, E) Representative H&E staining of colon tissue sections and histological score in each group, Scale bar, 200μm (n=6, Kruskal-Wallis test). (F) In vivo imaging of FITC-Dextran leakage. **p < 0.01, compared with Control group. #p < 0.05, ##p < 0.01, compared with MTX group.
