Table 2. Relative Changes in Capacitance Values of Different Membrane Compositions after Quinacrine Titration Derived from a Nonlinear Least Squares Fit to the EIS Data.
| ΔQ (μF sm–1) |
|||
|---|---|---|---|
| quinacrine (μM) | DOPC | DOPC:Chol | DOPC:SM:Chol |
| 0 | 0.0 | 0.0 | 0.0 |
| 1 | 0.04 ± 0.01 | –0.025 ± 0.01 | 0.215 ± 0.01 |
| 5 | 0.07 ± 0.02 | –0.016 ± 0.02 | 0.267 ± 0.07 |
| 10 | –0.05 ± 0.03 | –0.023 ± 0.01 | 0.272 ± 0.05 |
| 20 | –0.06 ± 0.04 | –0.047 ± 0.01 | 0.328 ± 0.51 |
| buffer exchange | 0.13 ± 0.03 | 0.144 ± 0.018 | 0.693 ± 0.14 |