Table 3.
Estimated vaccine effectiveness (VE) against laboratory-confirmed influenza (all subtypes) and influenza A(H1N1)pdm09 stratified for age groups, 2012–2016
| Season | Age group | Any influenza | A(H1N1)pdm09 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases (vaccin.) | Controls (vaccin.) | Crude VE in % (95% CI) | Adjusted*
VE in % (95% CI) |
Cases (vaccin.) | Controls (vaccin.) | Crude VE in % (95% CI) | Adjusted*
VE in % (95% CI) |
||
| 2012/13 | 2–17 | 1443 (67) | 1792 (146) | 45·1 (26·1–59·2) | 50·7 (32·5–64·0) | 278 (11) | 1792 (146) | 53·6 (13·1–75·2) | 56·7 (17·1–77·4) |
| 2–6 | 724 (33) | 1149 (76) | 32·6 (−2·6–55·7) | 37·1 (2·2–59·6) | 164 (7) | 1149 (76) | 37·1 (−39·0–71·5) | 33·1 (−52·8–70·7) | |
| 7–17 | 719 (34) | 643 (70) | 59·4 (37·9–73·4) | 57·8 (33·5–73·2) | 114 (4) | 643 (70) | 70·2 (16·8–89·4) | 73·2 (22·7–90·7) | |
| 2013/14 | 2–17 | 152 (16) | 1867 (144) | −40·8 (−142·8–18·4) | −4·3 (−2·9–40·5) | 27 (1) | 1867 (144) | † | † |
| 2–6 | 95 (9) | 1174 (75) | −53·3 (−216·8–25·8) | −25·5 (−165·5–40·7) | 18 (1) | 1174 (75) | † | † | |
| 7–17 | 57 (7) | 693 (69) | −26·6 (−190·1–44·7) | 8·8 (−114·0–61·2) | 9 (0) | 693 (69) | † | † | |
| 2014/15 | 2–17 | 940 (82) | 2071 (179) | −1·0 (−32·8–23·2) | 22·3 (−4·7–42·3) | 182 (15) | 2071 (179) | 5·1 (−64·6–45·2) | 9·3 (−62·0–49·3) |
| 2–6 | 495 (34) | 1225 (93) | 10·2 (−34·9–40·3) | 22·7 (−21·8–50·9) | 133 (9) | 1225 (93) | 11·7 (−79·5–56·5) | 21·3 (−67·7–63·0) | |
| 7–17 | 445 (48) | 846 (86) | −6·8 (−55·2–26·4) | 21·6 (−17·0–47·5) | 49 (6) | 846 (86) | −23·3 (−198·1–49·0) | −8·0 (−173·0–57·3) | |
| 2015/16 | 2–17 | 769 (44) | 1593 (122) | 26·8 (−4·5–48·7) | 49·4 (25·7–65·5) | 324 (15) | 1593 (122) | 41·5 (−1·5–66·2) | 60·2 (29·3–77·6) |
| 2–6 | 411 (22) | 972 (63) | 18·4 (−34·5–50·5) | 44·8 (4·6–68·0) | 219 (13) | 972 (63) | 8·9 (−68·6–50·8) | 44·8 (−6·9–71·5) | |
| 7–17 | 358 (22) | 621 (59) | 37·6 (−3·6–62·5) | 52·9 (18·4–72·8) | 105 (2) | 621 (59) | 81·5 (23·1–95·6) | 86·2 (41·3–96·7) | |
| 2012–2016‡ | 2–17 | 3304 (209) | 7323 (591) | 23·1 (9·4–34·7) | 33·0 (24·3–40·7) | 811 (42) | 7323 (591) | 37·8 (14·2–54·9) | 47·0 (25·7–62·2) |
| 2–6 | 1725 (98) | 4520 (307) | 17·3 (−4·5–34·6) | 27·8 (6·8–44·1) | 534 (30) | 4520 (307) | 18·3 (−20·2–44·5) | 34·6 (1·0–56·8) | |
| 7–17 | 1579 (111) | 2803 (284) | 32·9 (15·7–46·6) | 40·1 (23·0–53·4) | 277 (12) | 2803 (284) | 59·8 (27·4–77·8) | 63·6 (33·1–80·3) | |
Statisically significant estimates (95% confidence limits excluding zero) are printed in bold.
*
Adjusted for sex, age, month of illness onset and federal state.
†
No VE estimate because of a too small number of cases (<30).
‡
Adjusted estimates additionally adjusted for season.