Table 2.

Adjusted Cox proportional hazard models: hazard of death in drug-sensitive, pulmonary TB cases started on treatment in Greater Tzaneen sub-district, 2008–2015

	Hazard ratio	95% CI	P-value
All cases
Confirmed TB	Reference
Empirically treated TB	2·28	1·97–2·64	<0·001
Year of starting treatment	0·89	0·85–0·93	<0·001
Female	Reference
Male	1·10	0·95–1·28	0·12
HIV negative	Reference
HIV positive	2·36	1·93–2·88	<0·001
Age in years	1·02	1·01–1·03	<0·001
HIV positive cases only, 2008–2013*
Confirmed TB	Reference
Empirically treated TB	1·81	1·43–2·30	<0·001
Year of starting treatment	0·86	0·79–0·94	<0·001
Female	Reference
Male	1·20	0·94–1·53	0·15
Age in years	1·01	1·00–1·03	0·01
Log CD4	0·67	0·62–0·74	<0·001

^*2013 is the last year for which CD4 data are available; 1611 individuals had a documented CD4 count with median value of 155 cells/mm³.