Fig. 2.

Global analysis of the SEV Proteome from healthy or HIV infected participants who use or do not use cocaine. A Venn diagram showing common and unique proteins among the clinical groups. B Heatmap of the Jaccard coefficient depicting similarities and differences among clinical groups. C Protein counts and distribution among the clinical groups. Error bars represent S.E.M. of 6 pools (n = 2) per group. Group comparison was achieved with an ordinary one-way Anova test (Tukey correction); ns, not significant. D Pearson correlation depicting differences in the enrichment level of the SEV proteins among the clinical groups. E Gene ontology analysis (top-5 Terms) of the total SEV proteome (2306 proteins); orange, green and blue represent biological process, cellular component, and molecular function, respectively