TABLE 2.

Logistic Regression Models Regarding Elevated Liver Function Tests

Parameter	AST Increase	ALT Increase	GGT Increase
Sex (women)	0.820; 0.741‐0.907; P < 0.001	1.230; 1.130‐1.340; P < 0.0001	1.407; 1.272‐1.554; P < 0.0001
Age (10‐year intervals)	1.051; 1.001‐1.103; P < 0.05	0.820; 0.787‐0.855; P < 0.0001	1.126; 1.072‐1.183; P < 0.0001
Alcohol consumption	1.219; 1.084‐1.368; P < 0.001	1.296; 1.172‐1.432; P < 0.0001	1.699; 1.521‐1.897; P < 0.0001
High alcohol consumption	2.400; 1.903‐3.007; P < 0.0001	1.774; 1.414‐2.211; P < 0.0001	3.168; 2.546‐3.927; P < 0.0001
Current smoker	0.689; 0.598‐0.790; P < 0.0001	0.734; 0.656‐0.820; P < 0.0001	1.147; 1.012‐1.298: P < 0.05
Metabolic syndrome	1.526; 1.360‐1.711; P < 0.0001	2.044; 1.850‐2.259; P < 0.0001	2.284; 2.044‐2.552; P < 0.0001
LDL increase	0.989; 0.882‐1.107; P = 0.84	1.411; 1.286‐1.548; P < 0.0001	1.334; 1.199‐1.482; P < 0.0001
HDL decrease	1.444; 1.271‐1.636; P < 0.0001	2.290; 2.067‐2.535; P < 0.0001	1.476; 1.301‐1.671; P < 0.0001

Data are expressed as OR; 95% CI (n = 14,742). Data are adjusted for sex, age, high alcohol consumption, current smoker, metabolic syndrome, increased LDL, and decreased HDL. Alcohol consumption was defined as an average daily intake of ≥20 g for women and ≥30 g for men; high alcohol consumption was defined as >60 g/day in men and >40 g/day in women.