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. 2022 May 12;13:823707. doi: 10.3389/fendo.2022.823707

Table 1.

The characteristics of the EPIs and their mothers.

Before matching After matching
Male (No. = 240) Female (No. = 199) P value Male (No. = 148) Female (No. = 148) P value
Neonatal characteristic
Gestational age, weeks 26.7 (26.0, 27.3) 26.9 (26.1, 27.4) 0.115 26.9 (26.0, 27.4) 26.7 (26.0, 27.4) 0.916
Birth weight, g 918 (810, 1000) 870 (760, 950) <0.01 920 (810, 980) 883 (783, 984) 0.430
WWLST, No. (%) 83 (34.6) 90 (45.2) 0.023 63 (42.6) 66 (44.6) 0.725
Apgar score, No. (%)
1-min ≤3 26 (10.8) 10 (5.0) 0.027 9 (6.1) 9 (6.1) 1.000
1-min 4~7 81 (33.8) 67 (33.7) 0.986 52 (35.1) 46 (31.1) 0.459
5-min ≤7 42 (17.5) 28 (14.1) 0.329 25 (16.9) 20 (13.5) 0.418
Mechanical ventilation, No. (%) 200 (83.3) 140 (70.4) <0.01 119 (80.4) 109 (73.6) 0.167
Duration of mechanical ventilation, days 4.8 (0.7, 13.5) 2.7 (0.0, 9.1) <0.01 4.3 (0.5, 12.1) 3.0 (0.0, 10.0) 0.088
Maternal characteristic
Age≥35 years old, No. (%) 80 (33.3) 46 (23.1) 0.018 42 (28.4) 37 (25.0) 0.511
Cesarean section, No. (%) 79 (32.9) 71 (35.7) 0.544 49 (33.1) 41 (27.7) 0.312
IVF, No. (%) 95 (39.6) 85 (42.7) 0.507 57 (38.5) 65 (43.9) 0.345
Twin/multiple pregnancy, No. (%) 63 (26.3) 66 (33.2) 0.113 47 (31.8) 56 (37.8) 0.272
Any antenatal steroids, No. (%) 155 (64.6) 136 (68.3) 0.407 105 (70.9) 94 (63.5) 0.173
Complete-course antenatal steroids, No. (%) 69 (28.7) 84 (42.2) <0.01 60 (40.5) 51 (34.5) 0.280
Placental abruption, No. (%) 24 (10.0) 18 (9.0) 0.735 13 (8.8) 13 (8.8) 1.000
Placenta previa, No. (%) 16 (6.7) 12 (6.0) 0.786 8 (5.4) 10 (6.8) 0.627
Premature rupture of membranes, No. (%) 82 (34.2) 64 (32.2) 0.657 59 (39.9) 52 (35.1) 0.401
Chorioamnionitis, No. (%) 20 (8.3) 20 (10.1) 0.534 13 (8.8) 13 (8.8) 1.000
Intrauterine distress, No. (%) 9 (3.8) 7 (3.5) 0.897 8 (5.4) 5 (3.4) 0.395
Hypertensive disorder of pregnancy, No. (%) 27 (11.3) 38 (19.1) 0.021 19 (12.8) 17 (11.5) 0.722
Gestational diabetes mellitus, No. (%) 42 (17.5) 35 (17.6) 0.981 23 (15.5) 28 (18.9) 0.442
Cervical incompetence, No. (%) 43 (17.9) 34 (17.1) 0.820 30 (20.3) 25 (16.9) 0.455

Data are presented as median (IQR), or number (%); EPIs, extremely preterm infants; IVF, in vitro fertilization; WWLST, withholding or withdrawing life-sustaining treatment.