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. 2022 May 1;18(8):3209–3222. doi: 10.7150/ijbs.70289

Figure 6.

Figure 6

LncARSR activates the STAT3 pathway to facilitate macrophage M2 polarization. A-B. After overexpression or knockdown of lncARSR, the expression level of lncARSR and STAT3 were detected by RT-qPCR and Western blot. The expression level of STAT3 was higher in lncARSR overexpression group than the knockdown one with synchronous tendency (p<0.001). C-D. After the target gene STAT3 was knockdown by siRNA, CD206 and CD163 MFI of STAT3 knockdown group was lower than lncARSR overexpression group (p<0.01). STAT3 knockdown could rescue the effect of lncARSR. **P<0.01, ***P<0.001 vs NC.