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. 2022 May 1;18(8):3209–3222. doi: 10.7150/ijbs.70289

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LncARSR promotes tumor growth and induces macrophage polarization in vivo. A-B. Through animal fluorescence quantitative analysis, we found that the MFI (mean fluorescence intensity) value of nude mouse tumors in lncARSR-overexpression group was significantly higher than that of Caki implant group and control group (***P<0.001). C-D. We detected the expression of F4/80, CD206 and Ki67 in tumor specimens of nude mice by immunohistochemistry. We found that the tumor volume of nude mice was significantly increased and the expression levels of F4/80, CD206 and Ki67 were significantly increased by immunohistochemistry in the lncARSR overexpression group (***P<0.001).