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. Author manuscript; available in PMC: 2022 May 26.
Published in final edited form as: J Am Coll Cardiol. 2016 Aug 2;68(5):450–458. doi: 10.1016/j.jacc.2016.05.060

TABLE 3.

Multivariable Analysis for Noninvasive Testing

Noninvasive Testing
No
(n = 61,838)
Yes
(n = 5,323)
Adjusted OR
(95% CI)
p Value
Age group
 18–70 yrs 22,700 (36.71) 2,538 (47.68) Reference group
 71–85 yrs 25,098 (40.59) 2,224 (41.78) 0.85 (0.793–0.901) <0.0001
 >85 yrs 14,040 (22.70) 561 (10.54) 0.36 (0.327–0.399) <0.0001
Sex
 Female 29,580 (47.83) 2,379 (44.69) Reference group
 Male 32,258 (52.17) 2,944 (55.31) 1.05 (0.986–1.111) 0.13
Index year
 2011 22,501 (36.39) 1,911 (35.90) Reference group
 2012 21,578 (34.89) 1,907 (35.83) 1.04 (0.973–1.112) 0.25
 2013 17,759 (28.72) 1,505 (28.27) 0.99 (0.925–1.068) 0.87
Heart failure type
 Preserved ejection fraction 19,514 (31.56) 1,649 (30.98) Reference group
 Reduced ejection fraction 21,118 (34.15) 2,016 (37.87) 1.38 (1.282–1.491) <0.0001
 Mixed/unspecified 21,206 (34.29) 1,658 (31.15) 1.31 (1.208–1.422) <0.0001
Cardiovascular characteristics
 CAD 33,200 (53.69) 2,851 (53.56) 1.25 (1.172–1.329) <0.0001
 Hypertension 51,484 (83.26) 4,428 (83.19) 1.11 (1.024–1.202) 0.01
 Hyperlipidemia 28,866 (46.68) 2,546 (47.83) 1.09 (1.026–1.160) 0.005
 Diabetes 28,608 (46.26) 2,660 (49.97) 1.06 (0.994–1.120) 0.08
 Smoking 6,690 (10.82) 642 (12.06) 1.05 (0.956–1.146) 0.3200
 Prior stroke 6,532 (10.56) 420 (7.89) 0.82 (0.741–0.914) <0.0001
 PAD 14,159 (22.90) 1,042 (19.58) 0.95 (0.879–1.019) 0.15
 Major arrhythmia 7,769 (12.56) 591 (11.10) 0.86 (0.781–0.939) 0.001
 Nonmajor arrhythmia 37,377 (60.44) 2,705 (50.82) 0.79 (0.742–0.835) <0.0001
 Prior noninvasive ischemic work-up 11,248 (18.19) 594 (11.16) 0.56 (0.509–0.610) <0.0001
 Prior invasive ischemic work-up 7,529 (12.18) 356 (6.69) 0.49 (0.437–0.550) <0.0001
Comorbid conditions
 Renal disease 30,754 (49.73) 2,457 (46.16) 0.88 (0.826–0.930) <0.0001
 CABG 26,509 (42.87) 1,955 (36.73) 0.77 (0.728–0.821) <0.0001
 Malignancy 11,593 (18.75) 894 (16.80) 0.96 (0.891–1.038) 0.31
 Dementia 3,586 (5.80) 151 (2.84) 0.62 (0.521–0.731) <0.0001

Values are n (%) unless otherwise indicated.

CI = confidence interval; OR = odds ratio; other abbreviations as in Tables 1 and 2.