Table 2.
Sham | Sham + EMPA | TAC | TAC + EMPA | |
---|---|---|---|---|
Body weight (g) | ||||
Baseline | 27.7 ± 0.5 | 27.1 ± 0.4 | 29.6 ± 1.2 | 28.1 ± 0.8 |
6 weeks | 29.4 ± 0.4 | 28.2 ± 0.5 | 30.1 ± 0.8 | 28.0 ± 1.0 |
FBG (mg/dL) | ||||
Baseline | 91.7 ± 4.2 | 106.2 ± 8.2 | 94.3 ± 6.2 | 89.9 ± 3.4 |
6 weeks | 98.8 ± 8.6 | 101.7 ± 6.0 | 115.5 ± 5.1 | 107.7 ± 9.7 |
Results are expressed as mean ± SEM, n = 5–7. One-way ANOVA and Tukey post hoc test. FBG, fasting blood glucose; EMPA, empagliflozin; TAC, transverse aortic constriction; SEM, standard error of the mean.