Table 3. Logistic analysis for factors associated with substance use disorder.

Variable	Total sample				Before the pandemic		During the pandemic
	Bivariable analysis		Multivariable analysis		Bivariable analysis		Bivariable analysis		Multivariable analysis
	Crude Odds ratio (95% confidence interval)	p-value	Crude Odds ratio (95% confidence interval)	p-value	Crude Odds ratio (95% confidence interval)	p-value	Crude Odds ratio (95% confidence interval)	p-value	Adjusted odds ratio (95% confidence interval)	P-value
Age	1.86 (1.31–2.62)	<0.001	1.81 (1.31–2.52)	<0.001	1.98 (1.20–3.24)	0.007	1.76 (1.08–2.86)	0.023	1.72 (1.06–2.80)	0.028
Gender
Female	1				1		1
Male	Omitted				Omitted		Omitted
Schizophrenia and other primary psychosis (6A2)
No	1		1		1		1
Yes	0.77 (0.01–0.57)	0.012	0.03 (0.01–0.22)	0.001	Omitted		0.16 (0.02–1.28)	0.085
Bipolar mood disorders
No	1		1		1		1		1
Yes	0.09 (0.02–0.37)	0.001	0.04 (0.01–0.17)	<0.001	Omitted		0.19 (0.04–0.87)	0.032	0.18 (0.04–0.87)	0.032