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TEM image of (A) ZIF8 NPs, (B) H-L-D-Z NPs, and (C) H-L-D-Z@PM NPs. (D) UV–vis absorption spectra of ZIF8, Hb, LOX, DOX, PM, and H-L-D-Z@PM. (E) XRD pattern of ZIF8, H-L-D-Z, and H-L-D-Z@PM. (F) Hydrodynamic size distribution and (G) ζ potentials of ZIF8, H-L-D-Z, and H-L-D-Z@PM. (H) Oxygen-carrying and -releasing ability of ZIF8, H-L-D-Z, and H-L-D-Z@PM. (I) Effect of pH on the release of DOX from H-L-D-Z@PM.
