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. 2022 May 16;18(5):e1010540. doi: 10.1371/journal.ppat.1010540

Table 1. Clinical signs observed for all A. marginale vaccine study groups.

Steer number Clinical Signs Observed
Treatment Group Adjuvant Only 4493 • Inappetence (D23, 24, 27 PC)
4496 • Fever (104.6°F—D25 PC)
• Inappetence (D27 PC)
HH6 • Fever (104°F–D27 PC)
• Lethargy & Inappetence (D28 –D30 PC)
• Pale mucous membranes, Thin and watery blood, Jaundice onset (D29 PC)
• Animal euthanized prior to study completion–condition was not improving
Whole Cell Antigen Vaccine 4491 • Mild fever (103.2°F, D24)
4502 • Appeared normal
4505 • Mild fever (~103°F, D25 –D27)
• Reduced appetite (D30, 31 PC)
Modified Live Vaccine DP324 • Appeared normal
4506 • Appeared normal
HH5 • Appeared normal