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. 2022 May 16;18(5):e1009973. doi: 10.1371/journal.pgen.1009973

Table 1. Expression quantitative trait loci (eQTL) enrichment at atopic dermatitis (AD) risk loci.

Application of our regulatory element locus intersection (RELI) method [21] to 3,143 AD variants across 29 independent risk loci using eQTL data obtained from the Genotype-Tissue Expression (GTeX) database [22] and the Database of Immune Cell Expression, eQTL and Epigenomics (DICE) [23].

Cell line/track Overlap Corrected
P-value
Enrichment
CD4+ T cell: DICE 6/29 3.85 x 10−5 6.84
Sun-unexposed skin: GTEx 14/29 4.91 x 10−8 4.67
Sun-exposed skin: GTEx 10/29 2.9 x 10−4 4.19
Esophageal mucosa: GTEx 8/29 2.34 x 10−6 4.09