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. 2022 May 26;11:e71542. doi: 10.7554/eLife.71542

Figure 2. Aged mice show impaired regeneration in the digit tip amputation model.

Figure 2.

(A) Radiographic imaging from day 0 to day 42 (D0 to D42) in young and aged mice following amputation of the distal P3. (B) Masson’s trichrome staining of young and aged mice. (C) Micro-computed tomography (micro-CT) quantification of bone volume (relative to D0), trabecular thickness (Tb. Th.), and trabecular separation (Tb. S.) of regenerated bone over time. Graphs represent average values ± SD. n=4–14 digits/time point/age. *p<0.05.