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Characterization of CPM-DD. (A) Appearance (→ lyophilized powder, the cocktail solution of both drugs and copolymer, and the freshly prepared micellar solution), (B) Particle size distribution via DLS, (C) TEM imaging, (D) Temperature effect on particle size, (E), FBS effect on particle size, and (F) Drug release profile in vitro (pH 7.4).
