Table 1.
Baseline characteristics and surgical outcomes
| Total (n = 404) | Group A (newly diagnosed OSA n = 272, 67.4%) | Group B (pre-existing OSA, n = 132, 32.6%) | p | |
|---|---|---|---|---|
| Age (median, IQR) | 51 (45–57) | 51 (45–57) | 51 (46–58) | 0.605 |
| Gender, female (n, %) | 239 (59.2) | 182 (66.9) | 57 (43.2) | < 0.001 |
| BMI in kg/m.2 (mean, SD) | 43.1 ± 6.4 | 43.6 ± 6.3 | 42.3 ± 6.3 | 0.049 |
| Abdominal circumference, in cm (mean, SD) | 132 ± 14.7 | 132 ± 15.0 | 132 ± 13.9 | 0.868 |
| Medical history (n, %) | ||||
| Type 2 diabetes | 111 (27.5) | 70 (25.7) | 41 (31.1) | 0.465 |
| Hypertension | 202 (50) | 139 (51.1) | 63 (47.7) | 0.596 |
| Hypercholesterolemia | 132 (32.7) | 86 (31.6) | 46 (34.8) | 0.572 |
| GERD | 109 (27) | 78 (28.7) | 31 (23.5) | 0.285 |
| Asthma | 60 (14.9) | 28 (10.3) | 32 (24.2) | 0.001 |
| Chronic obstructive pulmonary disease | 17 (4.2) | 9 (3.3) | 8 (6.1) | 0.198 |
| Obesity hypoventilation syndrome | 2 (0.5) | 2 (0.7) | 0 | 0.280 |
| Chronic kidney disease | 17 (4.2) | 12 (4.4) | 5 (3.8) | 0.977 |
| History of psychiatric disorder | 131 (32.4) | 89 (32.7) | 42 (31.8) | 0.910 |
| HSAT outcomes | ||||
| REI (median, IQR) | 25.0 (17.6–40.3) | 23.4 (16.5–36.8) | 34 (20.0–52.4) | 0.001 |
| REI in supine position (median, IQR) | 31.3 (19,0–53.1) | 28.1 (17.9–46.8) | 45.0 (27.0–71.7) | 0.001 |
| ODI (median, IQR) | 25.7 (17.5–43.5) | 24.5 (17.2–39.5) | 34.6 (19.4–52.4) | 0.045 |
| Baseline saturation (median, IQR) | 93.0 (91.3–94.1) | 92.9 (91.2–94.1) | 93.0 (92.0–94.7) | 0.162 |
| Lowest saturation (median, IQR) | 79.0 (73.3–84.0) | 79.0 (73.0–84.2) | 81.5 (74.0–85.8) | 0.400 |
| Smoking (n, %) | ||||
| Current smoking | 19 (4.7) | 14 (5.1) | 5 (3.8) | 0.550 |
| History of smoking | 158 (39.1) | 103 (37.9) | 55 (41.7) | 0.444 |
| Type of Surgery (n, %) | ||||
| LRYGB | 302 (74.8) | 202 (74.3) | 100 (75.8) | 0.746 |
| LSG | 102 (25.2) | 70 (25.7) | 32 (24.2) | 0.747 |
| Complications < 30 days (n, %) | 37 (9.2) | 26 (9.6) | 11 (8.3) | 0.689 |
| Minor* | 21 (5.2) | 14 (5.1) | 7 (5.3) | 0.947 |
| Major * | 15 (3.7) | 12 (4.4) | 3 (2.3) | 0.403 |
| Cardiopulmonary complications | 4 (1) | 2 (0.7) | 2 (1.5) | 0.600 |
| ICU admission (n, %) | 9 (2.2) | 6 (2.2) | 3 (2.3) | 0.788 |
| Scheduled | 6 (1.5) | 4 (1.5) | 2 (1.5) | 0.972 |
| Unscheduled | 3 (0.7) | 2 (0.7) | 1 (0.8) | 0.980 |
| MCU admission (n, %) | 1 (0.2) | 1 (0.4) | 0 | 0.673 |
| Readmission (n, %) | 15 (3.7) | 12 (4.4) | 3 (2.3) | 0.568 |
| Reoperation (n, %) | 6 (1.5) | 6 (2.2) | 0 | 0.186 |
*Based on Clavien-Dindo classification (CDC); minor and major complications were defined as CDC 1–2 and CDC ≥ 3A
BMI body mass index, GERD gastroesophageal reflux disease, LRYGB laparoscopic Roux-en-Y gastric bypass, LSG laparoscopic sleeve gastrectomy, ICU intensive care unit, IQR interquartile range, MCU medium care unit, ODI oxygen desaturation index, OSA obstructive sleep apnea, REI respiratory event index, SD standard deviation