Table 3.

Univariable and multivariate logistic regression analysis of predictors for CPAP discontinuation (n = 397*)

	N (%)	Univariable		Multivariable
		OR [95% CI]	p value	aOR [95% CI]	p value
Gender (female)	239 (59.2)	0.74 [0.48–1.13]	0.160
Age ≥ 50 years	238 (58.9)	0.78 [0.51–1.21]	0.271
Preoperative BMI ≥ 45 kg/m2	127 (31.4)	0.53 [0.34–0.83]	0.006	0.43 [0.25–0.75]	0.003
Preoperative waist, in cm (mean, SD)	132 ± 14.7	0.99 [0.98–1.00]	0.165
Pre-existing diagnosis of OSA	272 (67.4)	3.10 [1.99–4.85]	< 0.001	2.93 [1.74–4.92]	< 0.001
Baseline REI ≥ 30	161 (42.2)	0.45 [0.29–0.70]	< 0.001	0.59 [0.37–0.95]	0.029
Asymptomatic before CPAP therapy	93 (23)	2.39 [1.28–4.46]	0.006	1.39 [0.74–2.63]	0.310
ESS ≥ 11**	111 (27.5)	1.022 [0.64–1.64]	0.927
Hypertension	202 (50)	0.99 [0.65–1.51]	0.972
Type 2 diabetes	111 (27.5)	0.58 [0.36–0.91]	0.018	0.55 [0.33–0.91]	0.021
Hyperlipidemia	132 (32.7)	1.30 [0.84–2.03]	0.245
Asthma	60 (14.9)	1.60 [0.90–2.82]	0.109
COPD	17 (4.2)	1.92 [0.73–5.11]	0.188
History of psychiatric disease	131 (32.4)	0.96 [0.61–1.51]	0.867
Current smoking	19 (4.7)	0.80 [0.31–2.09]	0.654
EWL ≥ 60%***	215 (53.0)	1.85 [1.20–2.84]	0.005	1.28 [0.66–2.47]	0.467
TWL ≥ 25%***	198 (49.0)	1.64 [1.07–2.52]	0.024	1.45 [0.79–2.63]	0.230

^*7 patients have missing data: 6 lost to follow-up and 1 fatality

^**Indicating mild excessive daytime sleepiness

^***Measured at six months postoperative

BMI body mass index, CI confidence interval, COPD chronic obstructive pulmonary disease, ESS Epworth Sleepiness Score, %EWL percentage excess weight loss, (a) OR (adjusted) odds Ratio, OSA obstructive sleep apnea, REI respiratory event index, %TWL Percentage Total Weight Loss