Table 4. Comparison of KOOS scores changes by months.

* p<0.05 **p<0.001

	Group A (n=40) Median (Min-Max)	Group B (n=42) Median (Min-Max)	P -value (Between Groups)
KOOS.S
At pre-injection	55.36 (25 - 93)	66.08 (32 – 100)	0.099
1st month	78.57 (32 – 100)	78.57 (25 – 100)	0.896
6th month	99.29 (56 – 100)	92.14 (53 – 100)	0.141
12th month	95 (49 – 100)	90 (53 – 100)	0.082
24th month 60th month	85 (39 – 100) 75 (25 – 100)	71.43 (43 – 100) 67.86 (36 – 100)	0.018* 0.449
KOOS.P
At pre-injection	38,9 (16,7 - 72,2)	47,2 (22,2 - 86,1)	0.058
1st month	63,9 (36,1 - 83,3)	66,7 (27,8 - 97,2)	0.985
6th month	90,8 (40 - 100)	92,2 (39,4 - 100)	0.757
12th month	86,7 (40,6 - 108,9)	78,9 (40,6 - 110)	0.014*
24th month	78,9 (25 - 115)	61,1 (30,6 - 98,3)	0.002*
60th month	65,3 (22,2 - 100)	55,6 (30,6 - 97,2)	0.379
KOOS.ADL
At pre-injection	41,2 (22,1 - 77,9)	45,6 (25 - 89,7)	0.053
1st month	66,2 (32,4 - 88,2)	64 (29,4 - 100)	0.692
6th month	90 (40 - 109,1)	90 (45,9 - 109,1)	0.329
12th month	86,3 (33,5 - 112,1)	80,6 (40,9 - 112,1)	0.049*
24th month	84,1 (23,5 - 115)	68,4 (30,9 - 106,2)	0.000**
60th month	64 (22,1 - 100)	59,6 (23,5 - 92,7)	0.565
KOOS.SP
At pre-injection	25 (5 - 55)	25 (0 - 80)	0.203
1st month	50 (10 - 75)	50 (0 - 95)	0.660
6th month	65 (10 - 105)	72,5 (10 - 100)	0.989
12th month	60 (5 - 100)	62,5 (5 - 100)	0.475
24th month	60 (0 - 100)	55 (0 - 95)	0.154
60th month	50 (5 - 100)	47,5 (0 - 95)	0.657
KOOS.QL
At pre-injection	25 (0 - 68,8)	37,5 (0 - 75)	0.121
1st month	50 (25 - 75)	53,1 (0 - 100)	0.925
6th month	65 (27,5 - 91,3)	72,5 (10 - 100)	0.639
12th month	66,3 (30 - 86,3)	67,5 (5 - 100)	0.738
24th month	60 (22,5 - 100)	55 (0 - 93,8)	0.068
60th month	43,8 (12,5 - 100)	46,9 (0 - 93,8)	0.678