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. 2022 May 26;12:212. doi: 10.1038/s41398-022-01968-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Pre-treatment correlation; B Post-treatment correlation; C Changes of treatment correlation. The altered IRF was considered to be a node in the network, and these nodes were connected by lines if there was evidence that they were associated by Pearson correlation analysis after Bonferroni correction. Pearson’s r and corrected p values were shown on the graph.