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. 2022 May 26;12:6468. doi: 10.1038/s41598-022-10899-1

Table 2.

Differential diagnosis of tuberculosis in individual A from “Casa del Fabbro”. nd: characteristic not determinable.

Lesion Individual A Actinomycosis Tuberculosis Brucellosis Osteoporosis Metastatic neoplasia Pyogenic osteomyelitis
Spinous process and neural arch are involved71,73 No No No No Yes Yes Yes
Large and spheroid lesions surrounded by reactive new bone72 No Yes No No No No No
First affects the peduncles70 No No No No No Yes No
Vertebral fracture73 No No Possible No Yes No No
Demineralization73 No No No No Yes No No
Vertebral bodies in lumbar tract affected71,73,74 Yes No Yes Yes Yes No Yes
Collapse of vertebral bodies and angular deformity74 Yes No Yes Yes No No No
At least two adjacent vertebrae affected in most of cases71 nd No Yes No No No Yes
Sign of Pedro-i-Pons74 No No No Yes No No No