Fig. 5. Sox2 overexpression impairs intestinal identity in adult homeostasis.

a–d Immunofluorescence images of Villin^+/+;R26^{Sox2-IRES-GFP +} (n = 3, left) and Villin^CreERT2/+;R26^{Sox2-IRES-GFP} (n = 4, right) for a SOX2 (red) and GFP (green), b CDX2 (red) and GFP (green), c Lysozyme C (LYZ, red) and GFP (green), and d OLFM4 (red) and GFP (green). Scale bars of a–d are 100 µm for top panels and 50 µm for bottom panels. White dotted boxes indicate areas of GFP expression.