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. 2022 Apr 15;30(7):6163–6173. doi: 10.1007/s00520-022-07038-x

Table 5.

The association between percentage weight loss and cumulative nutritional impact symptoms (NIS) and cumulative NIS interfering with oral intake at each follow-up. β is the — slope in association, as estimated from marginal trends derived from a mixed model for repeated measures. The value of β represents the expected change in percentage weight loss when increasing one point on the total NIS scale (range 17 to 85)

β 95% CI p-value
Lower Upper
NIS score
Follow-up 7 weeks  − 0.179  − 0.243  − 0.014  < 0.001
Follow-up 6 months  − 0.353  − 0.486  − 0.238  < 0.001
Follow-up 12 months  − 0.375  − 0.511  − 0.239  < 0.001
NIS interfering with oral intake score
Follow-up 7 weeks  − 0.126  − 0.174  − 0.0773  < 0.001
Follow-up 6 months  − 0.242  − 0.331  − 0.153  < 0.001
Follow-up 12 months  − 0.266  − 0.373  − 0.1595  < 0.001