. 2022 Feb 1;44(2):897–923. doi: 10.1007/s11357-021-00489-w

Table 3.

Imputed FI statistics — cellwise simulated missingness

Imputation	Type	Mean¹	Bias rate^2,3	SD¹	SD bias rate^2,3	HR¹	AUC^1,4
GT	–	0.176	0.000(0)	0.073	0.000(0)	1.075(7)	0.733(36)
Ignore	cMCAR	0.176	0.000(1)	0.076	0.014(1)^∗∗∗	1.070(7)	0.728(37)
Ignore20	cMCAR	0.176	0.000(1)	0.075	0.013(1)^∗∗∗	1.071(9)	0.729(41)
Default (m = 5)	cMCAR	0.193	0.109(1)^∗∗∗	0.078	0.030(1)^∗∗∗	1.071(7)	0.734(37)
MICE RF (m = 5)	cMCAR	0.188	0.073(1)^∗∗∗	0.076	0.017(2)^∗∗∗	1.073(7)	0.734(37)
RF	cMCAR	0.177	0.004(0)^∗∗∗	0.074	0.006(0)^∗∗∗	1.074(7)	0.732(37)
kNN	cMCAR	0.179	0.012(1)^∗∗∗	0.072	− 0.009(0)^∗∗∗	1.076(7)	0.730(37)
CART (m = 5)	cMCAR	0.177	0.002(1)^∗∗	0.073	0.002(1)	1.075(8)	0.732(37)
CART (m = 15)	cMCAR	0.177	0.002(0)^∗∗∗	0.074	0.004(1)^∗∗∗	1.077(7)	0.733(37)
CART+Aux (m = 5)	cMCAR	0.177	0.000(1)	0.074	0.004(1)^∗	1.076(8)	0.735(37)
Ignore	cMNAR	0.198	0.142(1)^∗∗∗	0.080	0.046(0)^∗∗∗	1.069(7)	0.732(37)
Ignore20	cMNAR	0.202	0.137(0)^∗∗∗	0.081	0.050(1)^∗∗∗	1.069(7)	0.735(39)
Default (m = 5)	cMNAR	0.193	0.109(1)^∗∗∗	0.078	0.029(1)^∗∗∗	1.071(7)	0.733(37)
MICE RF (m = 5)	cMNAR	0.188	0.074(1)^∗∗∗	0.076	0.017(1)^∗∗∗	1.073(7)	0.734(37)
RF	cMNAR	0.177	0.004(0)^∗∗∗	0.074	0.006(0)^∗∗∗	1.073(7)	0.733(37)
kNN	cMNAR	0.179	0.012(1)^∗∗∗	0.072	− 0.009(0)^∗∗∗	1.076(7)	0.730(37)
CART (m = 5)	cMNAR	0.190	0.092(1)^∗∗∗	0.077	0.025(1)^∗∗∗	1.072(7)	0.735(37)
CART (m = 15)	cMNAR	0.190	0.092(1)^∗∗∗	0.077	0.023(1)^∗∗∗	1.074(7)	0.735(37)
CART+Aux (m = 5)	cMNAR	0.176	0.000(1)	0.074	0.002(1)	1.075(7)	0.731(37)

5,6

¹ At 15% missingness

² The bias rate is the theoretical bias at 100% missingness

³ p-value for t-test vs 0

⁴ p-value for vs Ignore; Ignore vs GT

⁵ See Supplemental Table SIII for additional results. See Supplemental Figure S8 for forest plot of HRs

⁶ Bold: noteworthy result

Statistical significance is indicated with * p < 0.05, ** p < 0.01, or *** p < 0.001.