Table 2.
Results of univariate and multivariable Cox proportional regression analysis of age group, tumor size, EOR, and PORT in the entire study population.
| Univariate Analysis | Multivariable Analysis | |||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age | ||||
| <65 years | 1 [Reference] | 1 [Reference] | ||
| ≥65 years | 2.73 (1.57–4.74) | 3.56 × 10−4† | 3.41 (1.86–6.23) | 6.81 × 10−5† |
| Size | ||||
| ≤4.9cm | 1 [Reference] | 1 [Reference] | ||
| >4.9cm | 1.77 (1.04–3.04) | 0.036† | 1.78 (1.01–3.16) | 0.048† |
| Extent of resection | ||||
| GTR | 1 [Reference] | 1 [Reference] | ||
| Biopsy | 2.62 (1.29–5.31) | 0.007† | 3.03 (1.43–6.44) | 0.004† |
| STR | 1.40 (0.77–2.53) | 0.262 | 1.23 (0.67–2.27) | 0.497 |
| PORT | ||||
| No/Unknown | 1 [Reference] | 1 [Reference] | ||
| Beam radiation | 1.29 (0.81–2.38) | 0.235 | 0.81 (0.44–1.49) | 0.503 |
†P < 0.05, statistically significant.
EOR, extent of surgery; GTR, gross total resection; STR, subtotal resection; PORT, postoperative radiotherapy.