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. 2022 May 13;12:875122. doi: 10.3389/fonc.2022.875122

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Copyright © 2022 Zhao, Jiang, Weisenthal, Ma, Botticelli, Zhou, Hedley-Whyte, Wang, Swearingen, Soberman, Klibanski and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of tumor suppressors induced by HDAC3 and 5’-AZA. (A) Induction of E2F1, P16^Ink4a by 5’-AZA and RGFP966. (B, C): The expression of EGR1 and PTEN (B), and CD40 and STAT1 (C) induced by 5’-AZA and RGFP966. **p < 0.001, ****p < 0.00001.