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. 2022 May 13;13:900055. doi: 10.3389/fimmu.2022.900055

Table 2.

Distribution of the warning signs of the groups according to Jeffrey Modell Foundation.

Criteria PID SID Control Group P
N % n % n %
Oral antibiotic Two or more months on antibiotics with little effect. No 53 54.1 33 51.6 192 96 <0.001
Yes 45 45.9 31 48.4 8 4
Abscess Recurrent, deep skin or organ abscesses No 89 90.8 60 93.8 199 99.5 <0.001
Yes 9 9.2 4 6.3 1 0.5
Growing Failure of an infant to gain weight or grow normally No 61 62.2 29 45.3 197 98.5 <0.001
Yes 37 37.8 35 54.7 3 1.5
Thrush Persistent thrush in mouth or fungal infection on skin No 55 56.1 34 53.1 188 94 <0.001
Yes 43 43.9 30 46.9 12 6
IV antibiotic Need for intravenous antibiotics to clear infections No 17 17.3 0 0 170 85 <0.001
Yes 81 82.7 64 100 30 15
Septicemia Two or more deep-seated infections including septicemia No 88 89.8 55 85.9 200 100 <0.001
Yes 10 10.2 9 14.1 0 0
PI in family A family history of PI No 73 74.5 60 93.8 196 98 <0.001
yes 25 25.5 4 6.3 4 2
Ear infection Four or more new ear infections within 1 year No 90 91.8 63 98.4 199 99.5 <0.001
Yes 8 8.2 1 1.6 1 0.5
Sinus infection Two or more serious sinus infections within 1 year No 89 90.8 63 98.4 198 99 <0.001
Yes 9 9.2 1 1.6 2 1
Pneumonia Two or more pneumonias within 1 year No 35 35.7 5 7.8 193 96.5 <0.001
Yes 63 64.3 59 92.2 7 3.5